Crystal structure of 4-benzyl­carbamoyl-1-methyl­pyridin-1-ium iodide: an efficient multimodal anti­viral drug
Drebushchak T.N., Kryukov Y.A., Rogova A.I., Boldyreva E.V.
Acta Crystallographica Section E: Crystallographic Communications, 2017, Volume 73, Pages 967-970.

DOI: 10.1107/s2056989017008155
РИНЦ: 30690576 
Ключевые слова:

crystal structure; drug; polymorphism.

In the title compound, [MeC5H4NCONHCH2C6H5]I or C14H15N2O+·I−, a cation and an anion form an ionic pair linked by a strong N—H...I hydrogen bond. In the crystal, ionic pairs linked by weak C—H...I hydrogen bonds form infinite ribbons along the crystallographic a axis. Polymorphism screening varying crystallization solvents (water, acetone 90%–water, ethanol 90%–water, 2-propanol 90%–water, DMF, DMSO, methanol, aceto­nitrile) and conditions (solution temperature, heating and cooling protocols) did not reveal any other polymorphs than the one reported in this work.